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Audi Q5 Vs. Lexus RX 350 Vs. Acura MDX: Price, Performance, Dimensions

Audi Q5 vs Lexus RX 350 vs Acura MDX

Your luxury SUV shopping list likely involves comparing the 2025 Audi Q5 vs. Lexus RX 350 vs. Acura MDX. Each model offers a distinct blend of style, performance, and cutting-edge technology, making them top contenders in the luxury segment. The competition is strong, but so is the Lexus RX 350.

This competitive SUV is here to provide comfort and connectivity for the whole family. That's only the beginning, as you'll find many more attractive benefits. Whether you're still deciding or are looking to get one last taste before driving the Lexus model home, Bell Lexus has put together a guide on how the Lexus 350 compares in areas that enhance your daily drive.

 

Lexus RX 350 vs. Audi Q5 vs. Acura MDX at a Glance

  • Body Style: The Lexus RX, Audi Q5, and Acura MDX are all classified as luxury crossover SUVs, offering a great balance of comfort, space, and versatility.
  • Performance: The Lexus RX significantly outperforms the Audi Q5 in horsepower and torque and the Acura MDX in torque, with 275 horsepower and 317 pound-feet of torque.
  • Space: The Lexus RX boasts more standard cargo space than the other SUVs, plus more front and rear headroom than the larger Acura MDX.

Luxury Showdown: Audi Q5 vs. Lexus RX 350 vs. Acura MDX

Let's dive into the key highlights of each vehicle to see which one stands out in this ultimate luxury showdown, starting with the 2025 Lexus RX 350.

Known for its exceptional blend of reliability and sophistication, the RX 350 offers a sleek design, a well-appointed interior, and a host of advanced safety and tech features. A new Lexus RX 350 for sale starts at a more value-packed price than the others, too, meaning it provides more luxury amenities than the competitors, plus more standard cargo space and drivetrain options.

Lexus designers have provided a blend of SUV capabilities and luxury for a competitive price, knowing full well that the luxury SUV segment is fiercely competitive. However, the Lexus RX 350 has another leg up in this regard: market experience.

This model debuted in 1998. Meanwhile, the Audi Q5 vs. Lexus RX 350 comparison reveals that the Audi Q5 debuted in 2009 and the Acura MDX in 2001. The others are luxurious, but the new Lexus RX 350 draws on more than 25 years of experience. All the little things that form a luxurious experience were crafted with an eye for fine detail.

That level of detail applies to the full trim lineup of Lexus RX models. You can outfit the base-level choice with competitively high-end features. Here are some in-depth specs to compare:

2025 Lexus RX 350
Lexus RX 350
Standard Engine 2.4L 4-cyl Turbo
Horsepower 275
Torque 317 lb-ft
Avaiable With AWD? Yes
EPA-Est. MPG (City / Hwy) 22 / 291
2025 Audi Q5
Audi Q5
Standard Engine 2.0L 4-cyl
Horsepower 201
Torque 236 lb-ft
Avaiable With AWD? Yes
EPA-Est. MPG (City / Hwy) 23 / 292
2025 Acura MDX
Acura MDX
Standard Engine 3.5L V6
Horsepower 290
Torque 267 lb-ft
Avaiable With AWD? Yes
EPA-Est. MPG (City / Hwy) 19 / 263

 

Acura MDX vs. Lexus RX 350 vs. Audi Q5: Performance & Fuel Economy

When drivers compare the Lexus RX 350 to the Audi Q5 or Acura MDX performance, the Lexus RX 350 handily beats the Audi Q5 in horsepower and torque and greatly outpaces the Acura MDX in torque.

2025 Lexus RX 350: The Lexus RX 350 boasts a 2.4-liter turbocharged four-cylinder engine that generates 275 horsepower and 317 pound-feet of torque. It also comes with efficient FWD as standard, has an Avaiable With AWD? system, and uses a delightfully smooth standard eight-speed automatic Electronically Controlled Transmission. The new 2025 Lexus RX 350 provides an EPA-estimated 22/29 MPG (City/Highway) in FWD.1

2025 Audi Q5: The Audi Q5 comes up short in terms of performance, only delivering 201 horsepower and 236 pound-feet of torque with its base engine. It has a tiny edge with fuel efficiency, delivering up to an EPA-estimated 23/29 MPG (City/Highway).2 However, the hybrid variant Lexus RX 350h can achieve up to an EPA-estimated 37/34 MPG (City/Highway).4

2025 Acura MDX: The Acura MDX falls behind with an EPA-estimated 19/26 MPG (City/Highway)3 and a torque output of just 267 pound-feet of torque. While it does offer more standard horsepower, a direct comparison of its top-tier model to the Lexus RX reveals the superiority of the RX, which delivers 366 horsepower compared to the 355 horsepower on the MDX.

 

Lexus RX 350 vs. Acura MDX vs. Audi Q5: Dimensions & Size Chart

Let's compare the Lexus RX 350 vs. Acura MDX vs. Audi Q5 dimensions to find which of these new SUVs for sale is the roomiest and has the most cargo room. Here's a look at the key measurements:

 

2025 Lexus RX 350
# of Passengers: 5
Length: 192.5 in
Width: 75.6 in
Height: 67.3 in
Standard Cargo Space: 29.6 cu ft
Headroom (Front / Second Row) 39.5 in / 38.6 in
Legroom (Front / Second Row) 41.1 in / 37.4 in
Hip Room (Front / Second Row) 56.7 in / 56 in
Shoulder Room (Front / Second Row) 58.1 in / 56.5 in
2025 Audi Q5
# of Passengers: 5
Length: 184.3 in
Width: 74.5 in
Height: 65.4 in
Cargo Space: 25.9 cu ft
Headroom (Front / Second Row) N/A
Legroom (Front / Second Row) N/A
Hip Room (Front / Second Row) N/A
Shoulder Room (Front / Second Row) N/A
2025 Acura MDX
# of Passengers: 7
Length: 198.4 in
Width: 78.7 in
Height: 67.9 in
Cargo Space: 16.3 cu ft
Headroom (Front / Second Row) 38.5 in / 38.1 in
Legroom (Front / Second Row) 41.6 in / 38.5 in
Hip Room (Front / Second Row) 59.3 in / 57.8 in
Shoulder Room (Front / Second Row) 61.9 in / 60.3 in

 

Keep in mind that while the three-row Acura MDX offers slightly more legroom, its larger size makes it less agile for navigating city streets. The Audi Q5 is more compact but keeps SUV shoppers in the dark by choosing not to publish interior measurements.

The Lexus RX 350 strikes a perfect balance among the three SUVs in terms of length, offering an ideal combination of maneuverability and interior space. Plus, the Lexus RX 350 offers the most standard cargo space, making it an excellent choice for anyone needing extra room for shopping bags or luggage.

Experience the 2025 Lexus RX 350 at Bell Lexus

The choice is entirely yours between the Audi Q5 vs. Lexus RX 350 vs. Acura MDX. If the many benefits that the Lexus RX 350 offers make it your winner, you can count on us to make driving one home an enjoyable experience. We can help keep it as enjoyable as the miles roll on; our service center is your trusted source for manufacturer-recommended maintenance and service. Stop by today and take a Lexus RX 350 for a spin with a test drive.

At Bell Lexus, we're committed to your satisfaction. From our service center to our finance department, we tailor the car-shopping experience around your unique needs, and in-depth model research is just one part of what our Lexus dealership offers you.

Frequently Asked Questions

Which is better: Lexus RX 350, Audi Q5, or Acura MDX?

Finding the better SUV will often be decided by personal taste, but the Lexus RX 350 offers many benefits over the competition. The new Lexus 350 for sale boasts a turbocharged engine and has better fuel economy and torque ratings than the 2025 Acura MDX. From luxury features to roomier interior measurements, you'll find a lot to love in the Lexus RX 350.

Is the Lexus RX 350 bigger than the Acura MDX?

The Lexus RX 350 is a spacious two-row SUV with five seats, while the three-row Acura MDX is a bigger SUV. The Acura MDX has a seven-passenger seating capacity. The vehicle provides more seats but offers less headroom than the Lexus RX 350 in the first and second rows. The Acura MDX also has less torque than the Lexus RX 350.

What is the difference between Lexus RX 350 and Acura MDX?

The main difference in a Lexus RX 350 vs. Acura MDX comparison is that the Acura MDX is a three-row SUV, while the Lexus RX 350 is a two-row SUV. Both are luxury vehicles, but the Lexus 350 is tailored around your comfort. It also offers a turbocharged engine with more torque and better fuel economy ratings than the Acura MDX.


Bell Lexus North Scottsdale is a premier dealership serving the Scottsdale area, offering new and pre-owned Lexus vehicles along with service, parts, and financing. Committed to transparency and convenience, they help customers spend less time researching and more time enjoying their Lexus.

Bell Lexus North Scottsdale

Additional Lexus Model Resources


1EPA-estimated 22 city/ 29 hwy/ 25 comb MPG rating for 2025 Lexus RX 350 FWD. Use for comparison purposes only. Your mileage will vary for many reasons, including your vehicle's condition and how/where you drive. See www.fueleconomy.gov.

223 city/29 highway/26 combined city/hwy MPG 2025 Audi Q5 40 TFSI. EPA estimates. Your mileage will vary and depends on several factors including your driving habits and vehicle condition.

3Based on 2025 EPA mileage ratings. Use for comparison purposes only. Your actual mileage will vary, depending on how you drive and maintain your vehicle, driving conditions, and other factors.

4EPA-estimated 37 city/ 34 hwy/ 36 comb MPG rating for 2025 Lexus RX 350h AWD. Use for comparison purposes only. Your mileage will vary for many reasons, including your vehicle's condition and how/where you drive. See www.fueleconomy.gov.